We had the pleasure of interviewing Ellen Pompeo who stars as Meredith Grey in the hit medical drama, Grey's Anatomy. With the season five DVD about to be released, we chat to the actress about her character's ever-changing relationship with McDreamy. Pompeo also opens to reveal her thoughts on marriage, children and big, puffy, white wedding dresses...

Is it true you were the first actor cast for Grey's Anatomy?

Ellen Pompeo: I'm not sure if I was the first person cast. However, I didn't audition for the show. I was offered the show by the network, so I did have a different journey through casting than most people on the show.

How tough was it to find an actor for the role of Derek Shepherd?

Ellen Pompeo: It wasn't tough, actually. The minute I read with Patrick Dempsey, I knew he was the one.

Looking back through the years, how did you find this chemistry - and did you imagine that you would come this far?

Ellen Pompeo: No, I don't think I ever imagined it would go this far, but you learn to trust your instincts. We had great chemistry together from the start. I felt something for him. I felt chemistry; I felt an energy. I don't know if I can explain it, but we're lucky that it is what it is. I trusted it and the network saw it - and here we are today.

McDreamy and Meredith seem to be closer than ever in season five, although Derek has a hard time proposing...

Ellen Pompeo: Yes, I would agree with that. But we have two more seasons to film, so they have to drag it out a little.

What has been the fan reaction on the street about Derek and Meredith getting together again?

Ellen Pompeo: Los Angeles is a very insulated place. I don't think anybody on the street here really cares about us at all. It's not until we step outside of Los Angeles that people come up and talk to me about the show. I think people here are very used to seeing actors, so they don't ask anything. However, I think fans want them to get married and move on.